Lab News

January 2024: Our perspective on the link between activity dyshomeostasis and sleep dysfunctions is accepted in Nature Reviews NeuroscienceIn this article, we discussed 2 basic questions: (1) Why hyperexcitability is limited to low-arousal states during the initial stages of AD? (2) What the link is between hyperexcitability and sleep disturbances in presymptomatic AD stages?

October 2023: Congrats to Shiri and the team for discovering a new circuit-level mechanism underlying hyperexcitability associated with low-arousal brain states in mouse models of Alzheimer’s disease published in Nature Comm! We developed deep brain stimulation (DBS) of the thalamic nucleus reuniens to boost cognitive, neuronal and synaptic resilience to Alzheimer’s disease pathology. We are thankful to Nadav Buchbinder, Ortal Shinikamin, and Halit Baeloha for their invaluable contribution and to our collaborators Or Gold and Naomi Habib for snRNAseq analysis.

October 2023: Noa Elbaz – welcome to our lab for MSc studies!

March 2023: Congratulations to Inna for receiving the ERC Advanced Grant! This funding will enable us to investigate the intricate relationship between neuronal activity homeostasis, brain states, and memory impairments in Alzheimer’s disease.

September 2022: Dudi Mandil – welcome to the lab for MD/PhD studies!

June 2022: Our PNAS paper is out! Congrats to Max for discovering mitochondrial IGF1 receptors and their role in regulation of mitochondrial Ca2+ and firing rate homeostasis! We are grateful to Ilana Shapira and other lab members who contributed to this work and to our great collaborators – laboratories of Silvio Rizzoli, Eugenio  Fornasiero and Martin Holzenberger!

May 202: Lior, Neta and Dema – welcome to the lab as Sagol Fellows!

February 2022: Congrats to Tomer for receiving Zuckerman PostDoc Fellowship! @stem_program

January 2022: Congrats to Leore for publication of STAR protocols on recording of synaptic transmission and plasticity in behaving mice! It was a great team effort with Shiri Shoob, Lior De Marcas and Daniel Zarhin!

January 2022: Congrats to Daniel and Refaela! Our first in vivo work on dysregulation of neural activity during NREM sleep and general anesthesia in presymptomatic Alzheimer’s mouse models is finally published in Cell Reports! We are grateful to all our lab members who contributed to this work and to our great collaborators – laboratories of Yaniv Ziv, Yuval Nir, Tami Geiger, and Takaomi Saido!

February 2021: Congrats to Tomer Langberg for receiving Sagol Postdoctoral Fellowship!

January 2021: Congrats to Tomer for receiving Fulbright Postdoc Fellowship!

November, 2020: Congrats to Slutsky and Alessio Attardo labs for the joint DFG grant!

September 2020: Congrats to Tal Laviv for staring Assistant Professor position at TAU!

August, 2020: Welcome to Slutsky Lab, Tomer Langberg! Congrats for receiving Fulbright Postdoctoral Fellowship!

June 2020: Congrats to Maxim for receiving Glazer Fellowship of Excellence!

June 2020: Congrats to Slutsky and Tara Keck labs for the joint BIRAX ageing grant!

May, 2020: Congrats to Slutsky and Silvio Rizzoli labs for the joint DFG grant!

June 12 , 2019: Congrats to Boaz and Daniel for winning the best publication awards! 

May 2019: Congrats to Inna and Prof. Silvio Rizzoli for receiving Volkswagen grant for research Cooperation Lower Saxony – Israel.

April 29, 2019: Congrats to Boaz, Nir and Daniel! After 4 years of very intensive work, our work on the regulation of firing rate set point is finally online in Neuron! We are grateful to all our lab members who contributed to this work and to our wonderful collaborators – laboratories of Eytan Ruppin, Tami Geiger, Moran Rubinstein and Dori Derdikman!

January 2019: Congrats to our collaborators, Joris De Wit and Bart De Strooper laboratories, for revealing the physiological role of sAPP/GABA(B1a)R interactions! 

December 2018: Congrats to Inna, Naomi Habib (HUJI) and Orly Reiner (WIS) for receiving the MOST China-Israel Flagship Project in Brain Sciences!

December 2018: Leore and Ortal – welcome to the Slutsky Lab!

October 2018: Shiri and Nadav – welcome to the Slutsky Lab!

July 31, 2018: Farewell party for Neta who is starting PostDoc in Dr. Stephan Lammel lab at Berkeley!

February 5, 2018: Congrats to Boaz – our perspective on FHP hypothesis is online in Nature Neuroscience! 

January 3, 2018: Contgrats to Sam – our review on Alzheimer’s disease is online in Neuron!

July 2, 2017: Congrats to Neta for receiving Sackler faculty best publication award!

May 18, 2017: Eve Marder received a honorary doctorate in TAU!

eveDecember 19, 2016: Slutsky lab received Sackler excellence award!

December 8, 2016: Gabi and Ira received BrainBoost postdoctoral fellowships!

November 30, 2016: Inna received ERC consolidator grant!

2016: Congrats to Inna for receiving 2016 MetLife Foundation Award for promising research in Alzheimer’s disease. [English] [Hebrew] 


July 5, 2016: Nir received TEVA doctoral fellowships!

June 29, 2016: Congrats to Inna for receiving teaching excellence award!

May 23, 2016: Congrats to Neta for receiving Sieratzki Prize for the best publication among PhD students!


December 18, 2015: Congrats to Neta on two occasions: she got a new baby and a paper in Neuron in one week! Here is our video abstract [IGF-1R]

September 16, 2015: Congrats to Slutsky lab for winning Sackler Faculty of Medicine Excellence Award for publishing in the highest impact journals! Ira and Boaz received travel awards for best publications!

June 2, 2015: Congrats to Edden for receiving best publication award among MD/PhD students!

May 14, 2015: Congrats to Ira! Our paper on the role of GABABRs in firing rate homeostasis has been accepted in PNAS.

May 14, 2015: Congrats to Boaz for winning 2015 Gertner Fellowship of excellence!

December 31, 2014: Congrats to Edden and Boaz!

Edden Slomowitz and Boaz Styr

Our paper on the interplay between population firing stability and single neuron dynamics has been accepted in eLife. This work demonstrates that invariant ongoing population dynamics emerge from intrinsically unstable activity patterns of individual neurons and synapses. Moreover, it challenges cell-autonomous theory of network homeostasis and suggests existence of network-wide regulation rules.

This work was a fruitful collaboration with Prof. Eli Nelken and Dr. Michael Slutsky.

May 2014: Distinguished Mentor Award to Inna.  

March 2014: Congrats to Hilla and Samuel! Oshik, Ilana and all the lab members and our collaborators who participated in this project!

Our paper on the mechanism underlying Aβ-induced presynaptic hyperactivity has been accepted in Cell ReportsIt demonstrates that APP homodimers constitute a presynaptic receptor for amyloid-beta. This work was a fruitful collaboration with structural biologist Prof. Joel Hirsch (TAU), biophysicists Prof. Ehud Isacoff and Dr. Shashank Bharill (UC Berkeley), biochemists Prof. Dominic Walsh and Tiernan O’Malley (Harvard).

March 2014: Congrats to Tania for receiving Dan David Scholarship!

February 2014: Congrats to Neta for receiving best presentation award of Sagol School for Neuroscience!

November 2013: Congrats to Samuel for receiving Marie Curie CIG grant!

 June 19, 2013: Brain panel at the 2013 Israeli President’s Conference  [Tomorrow]

May 10, 2013: Congrats to Iftach and Hilla for receiving Sieratzki prize for the best publication!

April 25, 2013: Congrats to Iftach and Hilla!

Our paper is finally out in Nature Neuroscience! It demonstrates   regulation of amyloid-beta 40/42 ratio by spiking patterns, filter properties of synapses and sensory experience.

[AFTAU News] [Hayadan -Hebrew]

April 25, 2013: Congrats to Iftach for the approval of his PhD thesis!

May 02, 2013: Congrats to Irena for receiving the National Network of Excellence in Neuroscience Post-Doctoral Fellowship Award!

August 2011: Congrats to Tal for linking structural reorganization withing the GABA(B)R-G-protein-Calcium channel signaling complexes and synaptic vesicle release in hippocampal boutons, published in J Neurosci!

July 2010: Congrats to Inbal and Tal for identifying the mechanisms underlying heterogeneity of synaptic vesicle release in hippocampal neurons, published in Neuron!

November 2009: Congrats to Efrat and Iftach for identifying the physiological role of amyloid-β in synaptic function, published in Nature Neuroscience!